Kuo-Fen Lee, Ph.D.
![](/-/media/legacy/legacy-and-pre-launch-image-edits/scholars/1997/kuo-fen-lee.jpg?la=es&h=200&w=150&hash=C28CBB750C8D99797A6C7D86B05FD750)
- Title
- Professor
- Department
- Clayton Foundation Laboratories for Peptide Biology
- Institution
- Salk Institute for Biological Studies
- Address
- 10010 North Torrey Pines Road
- City, State, ZIP
- La Jolla, CA 92037
- Phone
- (858) 453-4100 x1120
- [email protected]
- Website
- http://www.salk.edu/faculty/lee.html
- Research field
- Neuroscience
- Award year
- 1997
Research
My lab studies the genes and molecules that guide brain cell development. We have considerable expertise in producing mice to study the effects of specific genes on nervous system function. My lab focuses on how disruptions in development and maintenance of nerve cells and their supporting cells can contribute to neurodegenerative diseases, such as Alzheimer’s disease, neuroendocrine diseases, such as anxiety, and neuromuscular diseases. Using gene “knock-out” technology to delete or alter the genes of mice models we observe the physiological effects. This may speed up by decades the discovery of how abnormalities occur in how brain cells communicate with each other. The ultimate goal of this work is to develop therapies to prevent brain cell death and treat disorders.
Scholar Keywords
1997 Search Pew Scholars
- Andrew Camilli, Ph.D.
- Ann Marie Craig, Ph.D.
- Patrick Dolph, Ph.D.
- Anirvan Ghosh, Ph.D.
- Benjamin S. Glick, Ph.D.
- Roberta A. Gottlieb, M.D.
- Gregory J. Hannon, Ph.D.
- Xi He, Ph.D.
- Ann B. Hill, Ph.D.
- Gokhan S. Hotamisligil, M.D., Ph.D.
- Gail P. Jarvik, M.D., Ph.D.
- Stephen L. Johnson, Ph.D.
- Maurice J. Kernan, Ph.D.
- Daniel S. Kessler, Ph.D.
- Michael R. Koelle, Ph.D.
- Kuo-Fen Lee, Ph.D.
- Tom W. Muir, Ph.D.
- William C. Sha, M.D., Ph.D.
- Kristiina Vuori, M.D., Ph.D.
- Wilma M. Wasco, Ph.D.
- Philip B. Wedegaertner, Ph.D.
- Yixian Zheng, Ph.D.