Qing R. Fan, Ph.D.
![](/-/media/legacy/legacy-and-pre-launch-image-edits/scholars/2009/qing-fan.jpg?la=pl&h=376&w=300&hash=6ED60E504DEBE17253998391045017D9)
- Title
- Assistant Professor of Pharmacology and Pathology
- Department
- Department of Pharmacology
- Institution
- Columbia University
- Address
-
Physicians & Surgeons
Room 7-430, 630 W 168th Street - City, State, ZIP
- New York, NY 10032
- Phone
- (212) 342-0115
- [email protected]
- Website
- http://sklad.cumc.columbia.edu/pharm/cumc/profile_new.php?id=301
- Research field
- Structural Biology
- Award year
- 2009
Research
Our laboratory studies the molecular mechanisms by which G-protein coupled receptors (GPCRs) transmit signals across biological membranes. GPCRs represent the superfamily of transmembrane receptors that signal through heterotrimeric G-proteins. GPCRs recognize a diverse array of ligands, and are the targets for 50-60% of clinical drugs. We combine x-ray crystallography with various biochemical techniques to study these receptors with two general goals: (1) to determine the specificity of receptor-ligand interactions, and (2) to identify receptor activation mechanisms.
Scholar Keywords
2009 Search Pew Scholars
- Frank Alber, Ph.D.
- Diana M. Bautista, Ph.D.
- Jon P. Boyle, Ph.D.
- Zev D. Bryant, Ph.D.
- Jennifer G. DeLuca, Ph.D.
- Qing R. Fan, Ph.D.
- Kevin A. Janes, Ph.D.
- John K. Kim, Ph.D.
- Alexander Meissner, Ph.D.
- Charles G. Mullighan, M.D.
- Patrick J. Paddison, Ph.D.
- Joseph R. Pomerening, Ph.D.
- Nicholas J. Priebe, Ph.D.
- Melissa M. Rolls, Ph.D.
- Joshua W. Shaevitz, Ph.D.
- Ben Z. Stanger, M.D., Ph.D.
- R. Grace Zhai, Ph.D.