Mark Winey, Ph.D.
![](/-/media/post-launch-images/2015/09/winey-mark1x1.jpg?la=pl&h=570&w=570&hash=1F16AD023F813BF07A3760F075A7BB0C)
- Title
- Professor
- Department
- Department of Molecular, Cellular and Developmental Biology
- Institution
- University of Colorado Boulder
- Address
-
MCD Building
Campus Box 347 - City, State, ZIP
- Boulder, CO 80309-0347
- Phone
- (303) 492-3409
- [email protected]
- Website
- https://mcdb.colorado.edu/directory/winey_m.html
- Research field
- Cell Biology; Genetics
- Award year
- 1993
Research
Microtubule organizing centers (MTOCs) are eukaryotic cellular structures that nucleate microtubule formation and organize microtubules in 3D space. The poles of mitotic and meiotic spindles define a specific class of MTOCs called centrosomes. Cell cycle control of centrosome assembly is an important event that ensures that centrosomes are duplicated only once per cell cycle so a normal bipolar spindle is formed. Besides chromosome replication, this is the only precise duplication event during the cell cycle. The primary focus of the Winey lab is to understand the mechanisms underlying centrosome duplication. We are also interested in identifying centrosome components and understanding how these structures function in microtubule nucleation, in microtubule organization, and in other cellular processes. Much of our current work centers on proteomic approaches to identifying of MTOC components and the modifications of these components involved MTOC assembly or function.
Scholar Keywords
1993 Search Pew Scholars
- Jochen Buck, M.D., Ph.D.
- Maureen J. Charron, Ph.D.
- Robert C. De Lisle, Ph.D.
- Jan Erikson, Ph.D.
- Edwin L. Ferguson, Ph.D.
- Erol Fikrig, M.D.
- Manfred Frasch, Ph.D.
- Paul D. Gollnick, Ph.D.
- Shi Huang, Ph.D.
- Gary H. Karpen, Ph.D.
- Markus D. Meister, Ph.D.
- David Ron, M.D.
- Mark A. Saper, Ph.D.
- James L. Sherley, M.D., Ph.D.
- Jonathan S. Stamler, M.D.
- Michel Streuli, Ph.D.
- Rudolph E. Tanzi, Ph.D.
- Trevor Williams, Ph.D.
- Mark Winey, Ph.D.
- Sarah A. Woodson, Ph.D.