James B. Moseley, Ph.D.
![](/-/media/legacy/legacy-and-pre-launch-image-edits/scholars/2011/james-moseley.jpg?la=nb&h=1242&w=1656&hash=81A4355DBE9D3A9B6A2663CA40E2C806)
- Title
- Assistant Professor
- Department
- Department of Biochemistry
- Institution
- Dartmouth College
- Address
- 7200 Vail, Remsen 412
- City, State, ZIP
- Hanover, NH 3755
- Phone
- (603) 650-1159
- [email protected]
- Website
- http://dms.dartmouth.edu/moseley/
- Research field
- Cell Biology
- Award year
- 2011
Research
The goal of my research is to understand how cell geometry controls biological activities through the spatial organization of signaling components. My lab is focused on the long-standing question of how the size and shape of a cell can trigger cell cycle transitions, a connection that generates cell size checkpoints in a wide range of cell types. For this work, we use the fission yeast Schizosaccharomyces pombe as a model system because of its simple geometry and genetic tools. By combining multi-generational microscopy with controlled changes in cell shape, we seek to uncover how physical geometry can act as an “input” signal to direct the “output” function of a signaling cascade.
Scholar Keywords
2011 Search Pew Scholars
- Christine M. Dunham, Ph.D.
- Thomas G. Fazzio, Ph.D.
- Max L. Fletcher, Ph.D.
- Hunter B. Fraser, Ph.D.
- Melissa K. Gardner, Ph.D.
- Mary Gehring, Ph.D.
- Jeff Gore, Ph.D.
- Takaki Komiyama, Ph.D.
- Mei Kong, Ph.D.
- Michael S. Kuhns, Ph.D.
- Erica Larschan, Ph.D.
- Eros Lazzerini Denchi, Ph.D.
- Ann C. Morris, Ph.D.
- James B. Moseley, Ph.D.
- Suzanne M. Noble, M.D., Ph.D.
- Brad J. Nolen, Ph.D.
- Chad G. Pearson, Ph.D.
- Sharad Ramanathan, Ph.D.
- Anthony R. Richardson, Ph.D.
- Niels Ringstad, Ph.D.
- Georgios Skiniotis, Ph.D.
- Liang Zhou, M.D., Ph.D.