Eros Lazzerini Denchi, Ph.D.

Sections

Eros Lazzerini Denchi, Ph.D.
Title
Stadtman Investigator
Department
Laboratory of Genome Integrity
Institution
National Cancer Institute, National Institutes of Health
Address
37 Convent Dr, Bild 37, 2144B
City, State, ZIP
Bethesda, MD 20892
Phone
(240) 760-7031
Email
[email protected]
Website
https://irp.nih.gov/pi/eros-lazzerini-denchi
Research field
Stem Cell Biology
Award year
2011

Research

In our laboratory, we study the mechanisms by which DNA damage results in premature aging, with a focus on telomeric DNA damage. Damage to telomeres is particularly relevant for aging since it accumulates throughout the human lifespan, contributing to telomere dysfunction which is believed to be one of the underlying causes of aging-associated pathologies. Our goal is to identify the key physiological processes that lead to aging upon telomeric DNA damage-findings that will significantly impact public health and could reveal novel therapeutic approaches to aging.

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