On Oct. 5, 2016, 12 major health organizations issued a joint statement on the important role antibiotic stewardship plays in the fight against antibiotic resistance, and committed to collective action to ensure the appropriate use of these critical therapies. These organizations’ coordinated efforts are aimed at driving progress toward national targets to reduce unnecessary antibiotic prescriptions in the U.S. – released by the Centers for Disease Control and Prevention and The Pew Charitable Trusts earlier this year – and will help to preserve these life-saving therapies.